Studies on the mechanism of toxicity of the chlorinated dibenzo-p-dioxins.

Degradation of Chlorinated Dibenzofurans and Dibenzo-p-Dioxins by Sphingomonas sp. Strain RW1.

The ability of the dibenzofuran- and dibenzo-p-dioxin-mineralizing bacterium Sphingomonas sp. strain RW1 (R.-M. Wittich, H. Wilkes, V. Sinnwell, W. Francke, and P. Fortnagel, Appl. Environ. Microbiol. 58:1005-1010, 1992) to oxidize chlorinated derivatives of dibenzofuran and dibenzo-p-dioxin was analyzed. Strain RW1 degraded several mono- and dichlorinated dibenzofurans and dibenzo-p-dioxins, b...

Analytical and confirmative techniques for dibenzo-p-dioxins based upon their cation radicals.

A large number of analytical methods for the detection of chlorinated dibenzo-p-dio-xins have been reported in the past few years (1-8) ; generally, these methods involve the use of gas-liquid chromatography (GLC) or GLC coupled with mass spectrometry (MS). Detection limits of about 1 ng have been reported for GLC-MS techniques with the demonstrated capability of detecting these compounds in th...

QSAR Studies of the Dioxins and Interaction of OCDD with Calix[4] Arene Using DFT

Quantum chemical calculations, based on Density Functional Theory (DFT) method, were performed on Calix[4]arene and Polychlorinated Dibenzo-p-dioxins (PCDDs) in gas and liquid phases for comparison purposes. The simulation results show the 1,2,3,4, 6,7,8,9-octachlorodibenzo-p-dioxin (OCDD) is quite a reactive dioxin. This paper attempts to examine the possibility of dioxin adsorption by Calix[n...

Determination of chlorinated dibenzo-p-dioxins and dibenzofurans in various materials.

Mechanisms of the biological effects of PCBs, polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in experimental animals.

Polychlorinated biphenyls, certain polychlorinated dibenzo-p-dioxins and certain polychlorinated dibenzofurans cause a variety of biological effects in experimental animals. The mechanism of the induction of certain enzymes is perhaps best understood. That is, there is binding of certain chlorinated biphenyls, dibenzo-p-dioxins and dibenzofurans to a receptor, translocation of the compound-rece...